8/04/2009

Mesothelioma Law Firms Overview...

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Mesothelioma law firms are those with lawyers who have experience handling mesothelioma cases. Experienced mesothelioma law firms can evaluate your case to

* See if you may be entitled to any compensation
* Help you find out if as well as how you were exposed to asbestos
* Find out who may be responsible for your illnessWhen you work with an asbestos or mesothelioma law firm, they may consult you to provide completely the necessary information and a lawyer or team of lawyers'll research, evaluate, and prepare your case as warranted. They are familiar with some statutes of limitations, or time limits and other factors that may affect whether you have a mesothelioma lawsuit.

Mesothelioma law firms can act as an advocate for you so that you do not have to worry about courts and case details. If you or a loved one has mesothelioma, you may be focused on treatments and care giving. Mesothelioma law firms can take care of the leg work of a lawsuit for you so you can focus on spending time with your family.

Knowing you have an experienced mesothelioma law firm working for you to help you receive compensation in your time of need can be very comforting for you and your family. For a free mesothelioma case evaluation by an experienced law firm, contact us today.

The explosion of mesothelioma and other asbestos-related illnesses in the United States and abroad as made such litigation a legal career all its own. Over the past thirty years, some unfortunate trends in the U.S. -- the federal government's abdication of regulatory responsibility, unregulated laissez-faire corporate capitalism, inhuman and parasitic greed on the part of corporations, and the refusal and failure of the U.S. government to recognize health care as the right of all citizens -- have converged to make the largest caused of legal action in modern history.

It's worth considering that had the federal government taken its responsibility toward its working citizens more seriously by subjecting industry to stringent safety regulations and provided free health care to all citizens, the amount of litigation would be a small fraction of what actually is today.

Sadly, the damage is done, yet the federal government and courts still exhibit a strong tendency to side with corporate interests. Fortunately, the few conscientious progressives in Congress and a small army of determined litigators committed to principles of justice continue to fight for victims' rights to recover damages caused by corporate disregard for human life and well-being in the name of profits.

A Brief History

The egregiousness of corporate malfeasance becomes horribly clear when it is understood that the toxic properties of asbestos have been known and documented since the days of the Roman Empire. The Romans were fascinated by the "magic mineral" that would not burn, yet could be woven into fabric like cotton or wool. Patricians knew the price of working with the substance, however; what the modern world knows as asbestos-related illness was called "The Slaves' Disease" by the idle rich of Rome (1).

The modern history of asbestos litigation starts in the late 19th Century. After half a century of asbestos manufacture and use as a building material, physicians were starting to look increasing numbers of respiratory illnesses among those who worked with asbestos. By 1897, a medical study by physicians in Italy identified asbestos dust as the cause of an outbreak of respiratory disease in a community of asbestos weavers (2). The same cause and effect was identified in British asbestos factories during the first ten years of the 20th Century.

By the 1920's, studies in the U.S. showed that asbestos workers were dying prematurely at a significantly higher rate than the general population, and by 1940, it was clear that asbestos exposure was the cause behind such deaths. Nonetheless, this information was suppressed by corporations and the federal government for another quarter-century. After a 1977 discovery of what came to be known as "The Asbestos Pentagon Papers" at the corporate headquarters of the Raybestos-Manhattan Company however, the truth could no longer be hidden (3).

Accountability

Since that time, well over six hundred thousand court actions have been taken against asbestos manufacturers as well as companies who used asbestos products. Despite the usual efforts on the part of corporations to abdicate their responsibilities through manipulation of the legislative process, the right of victims to hold them accountable has so far been upheld (4).

While there are many law firms able to competently represent a plaintiff in an asbestos case, it is worthwhile to do some due diligence. Because of the long latency duration of mesothelioma, asbestosis and other asbestos-related disease, it requires a great deal of specialized knowledge and research in order to build a strong case. Often, gathering supporting evidence is a challenge; for this reason, it is best to select your representation from among a number of mesothelioma law firms. These firms typically have had a great deal of experience in asbestos litigation. To put it in colloquial terms, the attorneys who work for a mesothelioma law firm "know where the bodies are buried."

The fact is, successfully winning a plaintiff judgment in an asbestos case requires meticulous, time consuming research and the testimony of very specific witnesses. As told earlier, mesothelioma has a long latency period -- symptoms typically do not appear for anywhere from twenty to forty years after initial exposure. In that time period, businesses go under or are acquired by other businesses; memories become uncertain; witnesses disappear.

An increasing number of mesothelioma law firms are building and maintaining databases of information related to the asbestos industry, with digital archives of old documents, photographs, depositions and court records, and examples of case law and precedent. If the law firm you are considering has access to such a database, it is a good indication that they will be able to represent you successfully.

The best way to find good mesothelioma law firms is to contact the bar association in your state. They can refer you to a number of qualified firms and individuals.

The next step is to interview attorneys from at least three or four different firms. Before deciding upon legal representation, learn about the attorney's experience. How many asbestos cases has s/he handled? In how many of these cases did the judge find for the plaintiff? Will s/he be handling the case personally, or referring it to someone else? Is s/he or the firm wiling to represent you on a contingency basis? Will your case stand alone, or will it be part of a group action?

Once you've ascertained this information, it is a good idea to log onto martindale.com and check the firm's profile and rating (5).

Remember that monetary awards in mesothelioma can be huge, and thus pose a great attraction to less ethical elements in the legal profession. If someone in a pinstriped three-piece suit and $300 hairstyle hands you a card that says "You May Have Million-Dollar Lungs!," this is not someone you want to have handle your case.

Spending the extra time and effort to find a principled legal professional with your best interests in mind who understands asbestos litigation takes some detective work, but it is well worth the effort.

Dallas mesothelioma lawyer : mesothelioma attorney dallas...

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Choosing a Dallas Mesothelioma Lawyers to handle any legal dispute or other issue obviously requires important consideration before a decision on the right person or firm is made. The natural inclination will be to go to a known lawyer rather than a stranger. But if that person is not specifically equipped to handle the matter, in spite of the best of intentions it is likely to be mishandled and the case lost. It is better to get advice from known lawyers to acertain who will be the best lawyer to handle that particular case. They able to even give a personal recommendation. The integrity and ethics of the concerned lawyer are the most important factors to be taken into consideration after evaluating their competence. Lawyers or legal firms established in this line and known to get the best for their clients are the best choice for victims of Mesothelioma who are seeking redress.

Criteria to be considered in choosing a lawyer In sensitive issues like mesothelioma, it is important for the client to be completely at ease with the lawyer. The latter should be able to make the former feel totally free to discuss the problem in detail and at length. The client should feel fully confident in the lawyer and should not experience even the slightest doubt concerning commitment or competence. The client should make detailed enquiries about the character of the lawyer, and directly ask for certain information concerning the lawyers capability to handle mesothelioma cases. The first question to be asked is the number of years that the lawyer has been handling similar cases and how numerous such cases are being handled at that time. The method of charging legal fees and other expenses should be clarified.

The next step is to find out how many similar cases the lawyer has handled altogether and the percentage of successful cases. Details of all cases that were lost should be sought, and reasons for their inability to win those cases should be obtained. Details of cases that have gone into appeals and the

manner in which they were handles should be studied. Details of cases tried in court and those settled out of court should be studied. The client should ascertain whether the cases won were handled by this particular lawyer or whether they were handed over to another lawyer (or one from another firm) to be conducted. While the credit for successful cases will be taken personally, the accountability for unsuccessful cases may be concealed. At this point the client will have a reasonably good idea concerning the efficiency of the lawyer, and could decide whether to proceed further or not. If the details up to that point have been favorable, the next question to be asked is whether the case will be handled directly or whether it will be handed over to some other lawyer. If there is any possibility that the case may must be handled by another Dallas Mesothelioma Lawyers or firm either from the beginning or during the process, details of the concerned lawyer or firm should be obtained. If possible, they should be met and consulted.

Dallas Mesothelioma Lawyers There are many good lawyers in Dallas who handle mesothelioma cases. They generally handle cases related to sicknesses arising out of consumption, inhalation or contact with different toxic substances. Some of the better legal firms offer a team of lawyers who handle the case from beginning to end, even if it goes into appeal or out of court settlement. All the team members interact with the client personally to build up morale and confidence. They are trained to be sensitive to the emotional and psychological stress and strain that the client is likely to be experiencing. Residents of Dallas who need to file their cases in other areas could get the services of firms that have branches or associates in those areas. Some firms will consider the merits of a good case and conclude the trial in court rather than go for an out of court settlement.

The following is a record of a couple of Dallas Mesothelioma Lawyers who will handle mesothelioma cases. Though it is not exhaustive, it contains some of the more reputed names: FindLaw Legal Connection, Simmons Cooper LLC, Bailey Gaylen, Baron Budd, Law Office of John Couch, Cooney Conway, Roger G. Worthington. The following link will be useful: lawyers.findlaw.com/lawyer/firm/ Asbestos-Mesothelioma/Dallas/Texas Conclusion Residents of Dallas who are in the need of the services of a lawyer to handle mesothelioma cases will find it more comfortable to deal with a person known to them, preferably one who is nearby. There are several good lawyers located all over the city. Those from outside Dallas, who need the services of a lawyer to conduct the case in Dallas, can readily find good lawyers in their own area who have branches or associates in this city. Clients should get clear information on legal and other expenses involved, on the probable duration of time required to conclude the case, and a realistic idea on what will be the final amount in their hand after deducting expenses. Getting the opinion of other persons who have been through the same process will be a very good idea.

8/03/2009

Mesothelioma Prognosis and Placenta Growth Factor...

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Mesothelioma, like other cancers, grows as well as spreads through a process of angiogenesis, the growth of early blood vessels. Without a blood supply a mesothelioma tumor would starve and die. Vascular endothelial growth factor (VEGF) is a protein made by cells that stimulates new blood vessel formation. Therefore, treatments that slow down or interrupt VEGF in tumors could slow or stop the formation of blood vessels ("anti-angiogenesis") and thereby stop the growth and spread of cancer.
One type of VEGF is placenta growth factor (P1GF). A recent study investigated whether P1GF is over expressed in mesothelioma.1 If it is this could present a new therapeutic target. Specimens from twenty-seven patients with mesothelioma were compared with specimens from ten fit patients. The researchers found that P1GF was not expressed in the normal mesothelium of the healthy subjects. However, it was over expressed in eleven (41%) of the patients with mesothelioma.

In this study, the mean survival of the mesothelioma patients after extrapleural pneumonectomy (EPP) was 17 months, but the patients with the least P1GF expression survived the longest. In fact, no relationship was found between tumor stage and survival or between tumor stage and PIGF expression. This would suggest that P1GF plays a "pivotal role" in the recurrence and progression of mesothelioma after EPP.

There are many anti-VEGF therapies being tested in other cancers e.g. bevacizumab (Avastin), ranibizumab (Lucentis), sunitinib (Sutent), sorafenib (Nexavar), axitinib, and pazopanib. However, according to a study published in 2008 while anti-VEGF drugs can show therapeutic efficacy in animals and in some human cancers, "the benefits are at best transitory and are followed by a restoration of tumour growth and progression."2 Nonetheless, more recent studies suggest that P1GF is a promising target and might support alleviate therapeutic resistance for treatments that focus only on VEGF.3 In fact, in one recent study, "the administration of an anti-PlGF antibody was found to lead to a significant reduction of malignant mesothelioma cell survival."4
Although the science is just now developing, the understanding of the role of P1GF in mesothelioma and its achievable therapeutic targeting holds promise for mesothelioma sufferers.

Endnotes:
1. Pompeo E, et al., Placenta growth factor expression has prognostic value in malignant pleural mesothelioma. Ann Thorac Surg. 2009 Aug;88(2):426-31.

2. Bergers and Hanahan, Modes of resistance to anti-angiogenic therapy. Nature Reviews Cancer 8, 592-603 (August 2008).

3. Loges S, et al., "Antimyeloangiogenic" treatment for cancer by inhibiting PlGF. Clin Cancer Res. 2009 Jun 1;15(11):3648-53. Epub 2009 May 26.

4. Albonici L, et al., Placenta growth factor is a survival factor for human malignant mesothelioma cells. Int J Immunopathol Pharmacol. 2009 Apr-Jun;22(2):389-401.



Mesothelioma Doctors List...

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This is a record of physicians who reportedly treat mesothelioma patients. Their appearance on this website is not a recommendation. You should treat these doctors as you would any unknown physician and consult many questions about their experience with different mesothelioma patients.
ArizonaLinda Garland, M.D.
Arizona Cancer Center - Hematology/Oncology
Tucson, Arizona
Tel. 520-694-CURE (2873)

Dr. Garland is an oncologist and the Director of the Arizona Cancer Center Clinical Lung Program where one of her specialties includes Mesothelioma. For more information, click here.
Helen J. Ross, M.D.
Mayo Clinic, Hematology/Oncology
Scottsdale, Arizona
Tel. 1-800-446-2279

Dr. Ross is a Thoracic Oncologist and Associate Professor of Medicine at the Mayo Clinic. For more information, click here.
California
Robert B. Cameron, M.D.
UCLA Medical Center
Los Angeles, California
Tel. 310-794-7333

Dr. Cameron is the Director of Thoracic Oncology at UCLA Medical Center. He is board-certified in general surgery and cardiothoracic surgery. His research interests include lung cancer, esophageal cancer and mesothelioma. For more information, click here.
David Jablons, M.D.
UCSF Comprehensive Cancer Center
San Francisco, California
Tel. 1-800-888-8664 or 415-885-7777

Dr. Jablons is the Professor and Chief of the Section of General Thoracic Surgery at UCSF. He is Board Certified in General Surgery and Thoracic Surgery. For more information, click here.
Theirry Jahan, M.D.
UCSF Comprehensive Cancer Center
San Francisco, California
Tel. 415-567-5581

Dr. Jahan is an relate clinical professor of medicine at UCSF. He specializes in the treatment of lung cancer, mesothelioma, sarcomas and endocrine tumors and the use of multiple treatments. For more information, click here.
Connecticut
Graeme L. Hammond, M.D., F.A.C.S.
Yale University School of Medicine, Department of Surgery
New Haven, Connecticut
Tel. 203-785-2704

Dr. Hammond is a professor with the Department of Surgery at the Yale University School of Medicine in New Haven, Connecticut. He is board-certified in surgery and thoracic surgery. For more information, click here.
Florida
Lary A. Robinson, M.D.
H. Lee Moffitt Cancer Center & Research Institute at The University of South Florida
Tampa, Florida
Tel. 813-745-8412

Dr. Robinson is the Director of the Division of Cardiovascular and Thoracic Surgery at the H. Lee Moffitt Cancer Center. For more information, click here.
Massachusetts
Raphael Bueno, M.D.
Brigham and Women's Hospital, Division of Thoracic Surgery
Boston, Massachusetts
Tel. 617-732-6824

Dr. Bueno is the Associate Chief of the Division of Thoracic Surgery for Brigham and Women's Hospital. He is board certified in Surgery, Surgical Critical Care and Thoracic Surgery. His clinical interests include tracheal surgery, lung cancer and mesothelioma. For more information, click here.
David J. Sugarbaker, M.D.
Brigham and Women's Hospital, Division of Thoracic Surgery
Boston, Massachusetts
Tel. 617-732-6824

Dr. Sugarbaker is Chief of the Division of Thoracic Surgery at Brigham and Women's Hospital. Malignant pleural mesothelioma has been a central focus of Dr. Sugarbaker's clinical and laboratory research. For more information, click here.
Scott J. Swanson, M.D.
Brigham and Women's Hospital/Dana Farber Cancer Institute
Boston, Massachusetts
Tel. 617-732-6824

Dr. Swanson is board certified in Surgery and Thoracic Oncology and Thoracic Surgery. For more information, click here.
Nebraska
Dr. Brian Loggie
Creighton University School of Medicine
Omaha, Nebraska
Tel. 402-280-3273

Dr. Loggie is a Professor of Surgery, Chief of the Division of Surgical Oncology, and Director of the Cancer Biology Program at Creighton University School of Medicine. His special interest include: Peritoneal carcinomatosis and malignant ascites, and peritoneal mesothelioma. For more information, click here.
New York
Manjit Bains, M.D., F.A.C.S
Memorial Sloan Kettering Cancer Center
New York, New York
Tel. 212-639-7450

Dr. Bains is board certified in Surgery and Thoracic Surgery and has clinical expertise in mesothelioma. For more information, click here.
Lee M. Krug, M.D.
Memorial Sloan Kettering Cancer Center
New York, New York
Tel. 212-639-8420

Dr. Krug is a medical oncologist who specializes in the treatment of thoracic cancers. He is board-certified in internal medicine and medical oncology. His research is focused primarily on small cell lung cancer and mesothelioma. For more information, click here.
Valerie Rusch, M.D., F.A.C.S
Memorial Sloan Kettering Cancer Center
New York, New York
Phone: 212-639-5873

Dr. Rusch is a surgeon who treats patients with cancers of the lung, esophagus, mediastinum, and chest wall, including those with mesothelioma. She is board certified in surgery and thoracic surgery. For more information, click here.
Harvey I. Pass, M.D.
New York University Medical Center
New York, New York
Tel. 212-731-5414

Dr. Harvey Pass is the Director of the New York University Medical Center Division of Thoracic Surgery and is Chief of Thoracic Oncology. He is one of the world's leading authorities on mesothelioma. For more information, click here.
Robert N. Taub, M.D.
NewYork-Presbyterian/Columbia
New York, New York
Tel. 212-659-6815

Dr. Taub is Board Certified in Hematology, Allergy and Immunology, Internal Medicine and Oncology. Dr. Taub is involved in developing combined chemotherapeutic and surgical techniques to combat mesothelioma. For more information, click here.
North Carolina
David H. Harpole, Jr., M.D.
Duke University Health System
Durham, North Carolina
Tel. 919-668-8413

Dr. Harpole is Vice Chair of Faculty Affairs and a member of the Division of Cardiovascular and Thoracic Surgery in the Department of Surgery of the Duke University Health System. His clinical interests include thoracic oncology, and mesothelioma. For more information, click here.
Pennsylvania
Daniel Sterman, M.D.
University of Pennsylvania Medical Center
Philadelphia, PA 19104-4283
Tel. 215-614-0984

Dr. Sterman is Associate Professor of Medicine, Associate Professor of Medicine in Surgery, Director of Interventional Pulmonology, and Clinical Director, Thoracic Oncology Gene Therapy Program at the University of Pennsylvania Medical Center. He is involved in various studies involving mesothelioma. For more information, click here.
Texas
W. Roy Smythe, M.D.
Texas A&M University Health Sciences Center
Temple, Texas
Tel. 254-724-2595

Dr. Smythe is involved in the surgical diagnosis and treatment of mesothelioma patients at the Texas A&M University Health Sciences Center. For more information, click here.
Washington, D.C.
Paul H. Sugarbaker, M.D.
Washington Cancer Institute
Washington DC
Tel. 202-877-3627

Dr. Sugarbaker is the Director of the Program in Peritoneal Surface Malignancy at the Washington Cancer Institute. His clinical interests include mesothelioma. For more information, click here.
Washington State
Eric Vallieres, M.D.
Swedish Medical Center
Seattle, Washington
Tel. 206-215-6800

Dr. Vallieres is a thoracic surgeon with the Swedish Medical Center. He is board-certified in general surgery and thoracic surgery. His areas of interest and expertise include mesothelioma and pleural diseases. For more information, click here.

7/31/2009

Overview of Mesothelioma

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If you or someone you know has been diagnosed with mesothelioma, you need all the information you could get about the illness and treatment options. This mesothelioma information will give you a better understanding of what the disease is, what causes it and how it is treated.What is Mesothelioma?

Mesothelioma, or cancer of the mesothelium, is diagnosed in about 2,000 to 3,000 individuals in the United States each year, and is becoming more common over time.

The mesothelium is a type of tissue formed by cells that surround the chest cavity, abdominal cavity and heart cavity. It protects the organs of the body by producing a fluid that allows the organs to move, as the lungs must do during breathing.

The most common form of mesothelioma is well-known as pleural mesothelioma, which starts in the chest cavity. About 75 percent of all mesothelioma is of this type, while 10 percent to 20 percent starts in the abdomen (peritoneal mesothelioma). It is rare but not unknown to have a mesothelioma start in the heart cavity (pericardial mesothelioma) (1).

What Causes Mesothelioma?

Most people who develop mesothelioma get it caused by exposure to asbestos, which is a general name given to groups of minerals that could be separated into durable threads. Asbestos is resistant to heat, fire and chemicals and does not conduct electricity, so it has been used in many construction projects and in different uses through the years (2).

A person's risk of developing mesothelioma varies depending on how much asbestos that person has been exposed to and for how long. Many people who develop mesothelioma do so later in life, but it has been diagnosed in younger people and even in children.

Between 70 percent and 80 percent of all mesothelioma cases can be definitively traced back to asbestos exposure, and it is thought that the remainder are asbestos-caused, but without an evidence trail to prove it. Many studies have looked at the links between mesothelioma and asbestos workers.

The death rate from mesothelioma in people who worked with asbestos insulation was 344 times higher than the death rate in the general population. Research indicates that inside 15 years of initial exposure, about 6 percent of all asbestos workers over the age of 35 will die of the disease (3).

It is estimated that about 8 million Americans have been exposed to asbestos, either through occupational hazards, picking it up from the clothing of a family member or going to school or work in a building that contained asbestos. Its estimated that 10 percent to 15 percent of all public schools in America have asbestos in them - as many as 733,000 buildings (4).

Occupational exposure can come from working in the insulation, plumbing, electrical and construction industries, as well as from working with automotive brakes, boilers and in shipyards. People who do demolition work can also be exposed to asbestos, as well as people who live near asbestos factories or work in buildings where asbestos is present (5).

Most people don't contract mesothelioma until 30 to 45 years after their first exposure to asbestos, though the time between exposure and diagnosis can range from 10 to 65 years (6). This long latency period makes diagnosis more difficult, and also accounts for the continued incidence of mesothelioma even after asbestos became known as a threat; several patients who were exposed in 1960 are only now developing the disease. However, the incubation period is not always lengthy; particularly for children, it is possible to be exposed and become ill very quickly thereafter.

How does Asbestos Lead to Mesothelioma?

Asbestos is made of large numbers of tiny fibers that are easily inhaled by a person working with them. The body wants to break down and remove these foreign particles from the lungs, which causes inflammation.

The tiny asbestos particles can get into the smallest and most remote parts of the lungs and they can't be coughed out unless they stick to mucus in the air passages. They can also settle in the tissue around the chest cavity (pleura) or the stomach cavity (peritoneum), where they cause inflammation and lead to mesothelioma (7).

Asbestos fibers in the lungs can damage the organs by forming scar tissue, and the risk of lung cancer is seven times greater for people who have had asbestos exposure compared to people who have not had such exposure. In fact, the three main causes of death for people with intense asbestos exposure are this scarring of the lungs (also known as asbestosis), lung cancer and mesothelioma (8).

How is Mesothelioma Treated?

There are various factors that can impact how mesothelioma is treated, with what stage the cancer is in, the size of the tumor and whether it could be completely removed through surgery, the amount of fluid in the chest cavity, the type and location of the mesothelioma and the age and state of health of the patient (9).

Depending on all these factors, treatment can range from surgery to remove the tumor and a little of of the surrounding tissue, radiation treatment or chemotherapy, drug therapy or removal of part of the lung. There are many different combinations of treatments that are being used as part of clinical trials, including biologic therapy, which attempts to boost the immune system to preclude recurrences (10).

What are the Odds of Surviving Mesothelioma?

Mesothelioma is a very severe disease, with an average survival time of about one year after diagnosis. That's because it is often in a late stage by the time it is diagnosed. The rate of people with mesothelioma who are still alive five years after diagnosis is about 10 percent, but the rate is steadily increasing. Most doctors say the outlook is more favorable for people who are diagnosed today (11).

Working with a doctor who has experience treating mesothelioma, as well as getting as much mesothelioma information as you can, will go a long way toward giving you or your loved one the best possible prognosis.

 

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